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Finding Paths in Codex
With this tool you can specify one or more source cells + one or more target cells, set a minimum synapse threshold per connection, and get a matrix with shortest path lengths for all source/target pairs. From there, you can inspect / visualize the pathways between any pair of cells in detail.
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Visual Columns Mapping Challenge
If you are good at programming / data analysis / algorithms and like challenges read on! FlyWire is issuing its first Data Challenge. Data Challenge: A wiring diagram of a brain is modeled as a directed graph with weighted edges, where nodes represent neurons and edges represent synaptic connections (weight = # synapses). In this…
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FlyWire Winter ’23 Update
It’s officially the start of the fall and winter holidays here in the northern hemisphere. Time to break out the hot drinks and relax by the warmth of the computer while you do a little connectome exploration. It’s been a while since we updated the blog (and we’ll try to do this more frequently).ere is…
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How To Use FlyWire for Connectomics
Welcome to FlyWire, a community connectomics project that has mapped the entire adult Drosophila melanogaster (fruit fly) brain! For more information, see flywire.ai. Release 630 is the default view in FlyWire and contains reconstructions of the 127,978 neurons that were proofread in the Connectome publication <bioRxiv>. 72,403 (56%) of these cells have been typed or…
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Optic Lobe Tag Rally
The FlyWire connectome contains over 127,000 proofread cells, ~73,000 of which are in the optic lobes (OL). While ~50,000 cells in the brain have labels, as of this post (May 2023), only 27% of neurons in the optic lobes are labeled (~20K cells). We hereby request the help of all FlyWire community members to complete…
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One Year of Citizen Science in FlyWire
On April 28, 2022, the first citizen scientists were invited to FlyWire. Today, one year later the connectome nears completion and the flagship FlyWire publication is on the horizon. Our seventeen Flyers proofread 16,316 neurons and annotated 21,151 cells. Thank you for this truly phenomenal effort. The First annkri and bl4ckscor3 were the first Flyers…
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Hierarchical Cell Annotations in FlyWire
Guest post by Philipp Schlegel, Cambridge Connectomics/Jefferis Lab Dear FlyWire community, As promised during the town hall meeting on March 30, 2023, here is a neuroglancer link with a couple layers you might find useful: The annotation labels won’t work with the FlyWire neuroglancer (yet) but you should be able to drag & drop the other layers…
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Spring 2023 FlyWire Town Hall
You are cordially invited to the next FlyWire Town Hall this Thursday, March 30th at 11 am US ET. RSVP for Zoom link and to receive a reminder before the event starts at flywire.ai/townhall. The event will begin with remarks from Mala Murthy and Sebastian Seung. Sven Dorkenwald will next debut figures from the upcoming…
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How to find photoreceptors to proofread and label
Big thanks to FlyWire team member Szi-chieh for putting together this guide for finding photoreceptors! Introduction Drosophila has two chief motion detection pathways (reference): Since we have all Mi1 cells labeled in the left hemisphere, based on the motion detection pathways, we can work our way up using an individual Mi1 to locate its presynaptic…
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Make Paper Figures in FlyWire
FlyWire screenshots can be used in your Drosophila melanogaster publications. Here are some tips to easily set up your scene: Full screen 3D view Hover your cursor over the 3D part of the screen and hit SPACE. SHIFT+Click + Drag allows you to pan the camera. To remove the axis bars, use the keyboard shortcut:…